Motif ID: TFAP2{A,C}.p2

Z-value: 3.601


Transcription factors associated with TFAP2{A,C}.p2:

Gene SymbolEntrez IDGene Name
TFAP2A 7020 transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
TFAP2C 7022 transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TFAP2Achr6_-_10527772-0.282.9e-01Click!
TFAP2Cchr20_+_54637714-0.165.4e-01Click!


Activity profile for motif TFAP2{A,C}.p2.

activity profile for motif TFAP2{A,C}.p2


Sorted Z-values histogram for motif TFAP2{A,C}.p2

Sorted Z-values for motif TFAP2{A,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFAP2{A,C}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_39573363 6.757 NM_002220
ITPKA
inositol 1,4,5-trisphosphate 3-kinase A
chr3_-_130807865 5.874 NM_015103
PLXND1
plexin D1
chr15_+_64782468 4.904 SMAD6
SMAD family member 6
chr19_-_11452439 4.841 NM_001420
NM_032281
ELAVL3

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)

chr15_-_81113676 4.830 NM_030594
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr4_+_2031036 4.808 NM_178557
NAT8L
N-acetyltransferase 8-like (GCN5-related, putative)
chr12_+_109956210 4.480 NM_015267
CUX2
cut-like homeobox 2
chr3_-_129689394 4.334 NM_001145662
GATA2
GATA binding protein 2
chr19_+_540849 4.229 NM_001194
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr16_-_87535106 4.224 NM_175931
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr9_+_125813849 4.213 LHX2
LIM homeobox 2
chr9_+_94987032 4.129 NM_006648
WNK2
WNK lysine deficient protein kinase 2
chr1_+_1557419 3.941 NM_006983
MMP23B
matrix metallopeptidase 23B
chr12_+_2032649 3.846 NM_000719
NM_001129827
NM_001129829
NM_001129830
NM_001129831
NM_001129832
NM_001129833
NM_001129834
NM_001129835
NM_001129836
NM_001129837
NM_001129838
NM_001129839
NM_001129840
NM_001129841
NM_001129842
NM_001129843
NM_001129844
NM_001129846
NM_001167623
NM_001167624
NM_001167625
NM_199460
CACNA1C






















calcium channel, voltage-dependent, L type, alpha 1C subunit






















chr5_+_170668892 3.751 NM_021025
TLX3
T-cell leukemia homeobox 3
chr2_+_120820140 3.711 NM_002193
INHBB
inhibin, beta B
chr8_-_144583718 3.582 NM_201589
MAFA
v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
chr2_+_42128521 3.485 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr1_-_11674264 3.484 NM_001127325
MAD2L2
MAD2 mitotic arrest deficient-like 2 (yeast)
chrX_+_68641802 3.422 NM_015686
FAM155B
family with sequence similarity 155, member B
chr10_-_88116181 3.404 NM_017551
GRID1
glutamate receptor, ionotropic, delta 1
chr8_+_104582151 3.354 NM_001100117
RIMS2
regulating synaptic membrane exocytosis 2
chr3_+_182912769 3.254 SOX2
SRY (sex determining region Y)-box 2
chr10_+_94439658 3.225 NM_002729
HHEX
hematopoietically expressed homeobox
chr17_+_62391216 3.209 NM_014405
CACNG4
calcium channel, voltage-dependent, gamma subunit 4
chr4_-_41848874 3.198 BEND4
BEN domain containing 4
chr22_-_37569679 3.186


chr10_-_28074752 3.170 NM_173576
MKX
mohawk homeobox
chr5_+_149526533 3.157 NM_001804
CDX1
caudal type homeobox 1
chr14_-_64416307 3.128 SPTB
spectrin, beta, erythrocytic
chr1_+_41022066 3.113 NM_004700
NM_172163
KCNQ4

potassium voltage-gated channel, KQT-like subfamily, member 4

chr17_+_56831951 3.032 NM_005994
TBX2
T-box 2
chr2_-_47650973 3.020 NM_022055
KCNK12
potassium channel, subfamily K, member 12
chr18_+_53253775 3.020 NM_004852
ONECUT2
one cut homeobox 2
chr3_-_124650081 3.006 NM_183357
ADCY5
adenylate cyclase 5
chr12_+_52665196 2.989 NM_017409
HOXC10
homeobox C10
chr10_-_131652364 2.989 EBF3
early B-cell factor 3
chr3_+_50217692 2.983 NM_006841
SLC38A3
solute carrier family 38, member 3
chr7_-_100331417 2.977 NM_000665
NM_015831
ACHE

acetylcholinesterase

chr4_-_85638410 2.963 NM_006168
NKX6-1
NK6 homeobox 1
chr10_-_134449467 2.851 NM_177400
NKX6-2
NK6 homeobox 2
chr2_+_74595073 2.820 NM_016170
TLX2
T-cell leukemia homeobox 2
chr20_-_538909 2.810 NM_004609
TCF15
transcription factor 15 (basic helix-loop-helix)
chr17_+_45993338 2.780 NM_018896
NM_198376
NM_198377
NM_198378
NM_198379
NM_198380
NM_198382
NM_198383
NM_198384
NM_198385
NM_198386
NM_198387
NM_198388
NM_198396
NM_198397
CACNA1G














calcium channel, voltage-dependent, T type, alpha 1G subunit














chr22_-_37569962 2.775 NM_014293
NPTXR
neuronal pentraxin receptor
chr10_+_23521464 2.761 NM_178161
PTF1A
pancreas specific transcription factor, 1a
chr9_-_93751900 2.758 NM_004560
ROR2
receptor tyrosine kinase-like orphan receptor 2
chr11_-_60819110 2.742 VWCE
von Willebrand factor C and EGF domains
chr3_+_148610516 2.736 ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr1_+_95355415 2.716 NM_152487
TMEM56
transmembrane protein 56
chr2_-_45090025 2.662 NM_016932
SIX2
SIX homeobox 2
chr2_+_102602579 2.612 NM_003048
SLC9A2
solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr17_+_56832255 2.592 TBX2
T-box 2
chr20_-_21326046 2.585 NM_033176
NKX2-4
NK2 homeobox 4
chr20_+_20296744 2.579 NM_002196
INSM1
insulinoma-associated 1
chr4_+_4912272 2.561 NM_002448
MSX1
msh homeobox 1
chr16_+_2461500 2.553 NM_006181
NTN3
netrin 3
chr17_-_77512346 2.534 NM_178493
NOTUM
notum pectinacetylesterase homolog (Drosophila)
chr19_-_14177980 2.517 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr10_-_103525646 2.517 NM_006119
NM_033163
NM_033164
NM_033165
FGF8



fibroblast growth factor 8 (androgen-induced)



chr17_-_10042579 2.495 NM_201433
GAS7
growth arrest-specific 7
chr5_-_11956964 2.492 NM_001332
CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr17_+_29931880 2.473 NM_207313
TMEM132E
transmembrane protein 132E
chr8_+_1937711 2.471 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr2_-_42573980 2.446 KCNG3
potassium voltage-gated channel, subfamily G, member 3
chr3_+_71885890 2.443 NM_018971
GPR27
G protein-coupled receptor 27
chr20_+_19141364 2.441 SLC24A3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr19_+_12805747 2.437 MAST1
microtubule associated serine/threonine kinase 1
chr1_+_22909916 2.422 NM_004442
NM_017449
EPHB2

EPH receptor B2

chr9_+_128416542 2.417 NM_001174146
NM_001174147
NM_002316
LMX1B


LIM homeobox transcription factor 1, beta


chr1_-_31154023 2.388 NM_014654
SDC3
syndecan 3
chr17_-_44058612 2.382 NM_024017
HOXB9
homeobox B9
chr1_-_50661716 2.380 NM_032110
DMRTA2
DMRT-like family A2
chr5_-_11957127 2.359 CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr7_-_150306169 2.345 KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr3_+_129690735 2.307


chr13_+_24844084 2.306 NM_016529
ATP8A2
ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr22_+_28446288 2.293 NM_182527
CABP7
calcium binding protein 7
chr15_+_39008822 2.291 NM_019074
DLL4
delta-like 4 (Drosophila)
chr1_-_6162669 2.287 NM_015557
CHD5
chromodomain helicase DNA binding protein 5
chr21_+_33364420 2.268 OLIG1
oligodendrocyte transcription factor 1
chr1_-_110414756 2.266 NM_006492
ALX3
ALX homeobox 3
chr4_-_174687104 2.245 HAND2
heart and neural crest derivatives expressed 2
chr16_+_85158357 2.243 NM_005251
FOXC2
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr1_+_11674365 2.243 NM_198545
C1orf187
chromosome 1 open reading frame 187
chr16_+_88169612 2.238 NM_014427
NM_153636
CPNE7

copine VII

chr9_-_119217147 2.231 ASTN2
astrotactin 2
chr2_+_171280944 2.229 SP5
Sp5 transcription factor
chr17_+_8865547 2.224 NM_004822
NTN1
netrin 1
chr18_-_42590989 2.202 NM_013305
ST8SIA5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr2_+_176680251 2.184 NM_021192
HOXD11
homeobox D11
chr22_+_43476710 2.180 NM_181333
PRR5
proline rich 5 (renal)
chr11_-_60819273 2.178 NM_152718
VWCE
von Willebrand factor C and EGF domains
chr2_+_176695658 2.165 NM_014213
HOXD9
homeobox D9
chr1_+_2975590 2.154 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr4_+_48180033 2.142 NM_152679
SLC10A4
solute carrier family 10 (sodium/bile acid cotransporter family), member 4
chr1_+_235272324 2.129 NM_001035
RYR2
ryanodine receptor 2 (cardiac)
chr3_-_71886203 2.124 NM_001134649
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr15_+_30797466 2.116 NM_001191322
NM_001191323
NM_013372
GREM1


gremlin 1


chr20_-_62151216 2.112 NM_018419
SOX18
SRY (sex determining region Y)-box 18
chr13_+_111769913 2.111 NM_005986
SOX1
SRY (sex determining region Y)-box 1
chr22_+_43476755 2.101 NM_181334
PRR5-ARHGAP8
PRR5
PRR5-ARHGAP8 readthrough
proline rich 5 (renal)
chr9_+_125813672 2.100 NM_004789
LHX2
LIM homeobox 2
chr2_-_236741352 2.092 NM_001485
GBX2
gastrulation brain homeobox 2
chr16_+_166678 2.088 NM_000558
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr6_+_19945578 2.074 NM_001546
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr1_-_99242765 2.055 NM_001010861
NM_001037317
LPPR5

lipid phosphate phosphatase-related protein type 5

chr11_+_43920385 2.053 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr16_-_49742651 2.047 NM_002968
SALL1
sal-like 1 (Drosophila)
chr17_+_40655060 2.040 NM_005892
FMNL1
formin-like 1
chr19_-_54557450 2.015 NM_003598
TEAD2
TEA domain family member 2
chr19_+_10392128 2.013 NM_001111307
PDE4A
phosphodiesterase 4A, cAMP-specific
chr14_+_68796621 2.006 GALNTL1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1
chr16_-_19803606 2.004 NM_016235
GPRC5B
G protein-coupled receptor, family C, group 5, member B
chr14_+_69021149 2.003 NM_001161498
UPF0639
UPF0639 protein
chr11_-_1549719 1.996 NM_004420
DUSP8
dual specificity phosphatase 8
chr16_-_51138306 1.984 NM_001080430
TOX3
TOX high mobility group box family member 3
chr22_-_17891777 1.984 CLDN5
claudin 5
chr18_-_4445265 1.976 DLGAP1
discs, large (Drosophila) homolog-associated protein 1
chr4_+_185064799 1.966 STOX2
storkhead box 2
chr11_-_69299351 1.957 NM_002007
FGF4
fibroblast growth factor 4
chr5_-_134397740 1.948 NM_002653
PITX1
paired-like homeodomain 1
chr17_-_16335809 1.947 C17orf76
chromosome 17 open reading frame 76
chrX_-_139414890 1.945 NM_005634
SOX3
SRY (sex determining region Y)-box 3
chr13_-_101366995 1.940 NM_004115
FGF14
fibroblast growth factor 14
chr19_+_51059357 1.931 NM_004497
FOXA3
forkhead box A3
chr1_+_229365296 1.922 NM_001004342
TRIM67
tripartite motif containing 67
chr12_+_108636569 1.918 NM_032829
C12orf34
chromosome 12 open reading frame 34
chr10_-_131652007 1.906 NM_001005463
EBF3
early B-cell factor 3
chr5_-_1348103 1.905 NM_001193376
NM_198253
TERT

telomerase reverse transcriptase

chr4_-_5945596 1.894 NM_001014809
CRMP1
collapsin response mediator protein 1
chr3_+_182912405 1.894 NM_003106
SOX2
SRY (sex determining region Y)-box 2
chr7_+_94374862 1.892 NM_001166160
NM_017650
PPP1R9A

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr22_-_45311730 1.886 NM_014246
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr10_-_99780336 1.875 CRTAC1
cartilage acidic protein 1
chr8_-_57521702 1.875 NM_001135690
PENK
proenkephalin
chr14_-_76677711 1.873 ZDHHC22
zinc finger, DHHC-type containing 22
chr6_-_110786167 1.851 NM_001123364
C6orf186
chromosome 6 open reading frame 186
chr7_-_123460722 1.837 NM_001136002
TMEM229A
transmembrane protein 229A
chr11_-_61441536 1.836 NM_013401
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr19_+_39664706 1.828 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr7_-_150305933 1.826 NM_000238
NM_172056
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr12_+_2032964 1.820 CACNA1C
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr12_+_79995927 1.820 NM_024560
ACSS3
acyl-CoA synthetase short-chain family member 3
chr17_-_71747867 1.814 NM_052916
RNF157
ring finger protein 157
chr7_+_154943466 1.811 NM_001427
EN2
engrailed homeobox 2
chr15_+_82113813 1.808 NM_207517
ADAMTSL3
ADAMTS-like 3
chr2_-_219633481 1.803 NM_002181
IHH
Indian hedgehog
chr10_+_50488352 1.795 NM_003055
SLC18A3
solute carrier family 18 (vesicular acetylcholine), member 3
chr5_+_129268352 1.792 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr15_-_49174107 1.790 TNFAIP8L3
tumor necrosis factor, alpha-induced protein 8-like 3
chr11_-_63292688 1.790 NM_001144936
C11orf95
chromosome 11 open reading frame 95
chr4_-_174686918 1.783 HAND2
heart and neural crest derivatives expressed 2
chr19_+_1704661 1.776 NM_001080488
ONECUT3
one cut homeobox 3
chr6_+_5030718 1.774 NM_001145115
PPP1R3G
protein phosphatase 1, regulatory (inhibitor) subunit 3G
chr20_-_61108831 1.765 NM_080606
BHLHE23
basic helix-loop-helix family, member e23
chr1_+_226937732 1.764 RHOU
ras homolog gene family, member U
chr9_-_95757365 1.764 NM_021570
BARX1
BARX homeobox 1
chr11_+_65311104 1.760 NM_004561
OVOL1
ovo-like 1(Drosophila)
chr22_-_37180958 1.759 NM_152868
KCNJ4
potassium inwardly-rectifying channel, subfamily J, member 4
chr7_-_35260213 1.745 NM_001077653
NM_001166220
TBX20

T-box 20

chr4_-_13155135 1.743 NM_001189
NKX3-2
NK3 homeobox 2
chr5_+_76542461 1.741 NM_001029851
NM_001029852
NM_001029853
NM_001029854
NM_003719
PDE8B




phosphodiesterase 8B




chr3_+_185580554 1.733 NM_003741
CHRD
chordin
chr1_+_63561632 1.732 FOXD3
forkhead box D3
chr2_+_241586927 1.728 NM_001080437
SNED1
sushi, nidogen and EGF-like domains 1
chr6_-_117193505 1.727 NM_001085480
FAM162B
family with sequence similarity 162, member B
chr2_-_42574587 1.719 NM_133329
NM_172344
KCNG3

potassium voltage-gated channel, subfamily G, member 3

chr1_-_114497994 1.718 NM_205848
SYT6
synaptotagmin VI
chr11_-_18769703 1.712 NM_001039970
NM_006906
NM_032781
PTPN5


protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)


chr6_+_99389318 1.703 POU3F2
POU class 3 homeobox 2
chr14_-_100104014 1.694 NM_001159531
BEGAIN
brain-enriched guanylate kinase-associated homolog (rat)
chr4_-_123092358 1.692 NM_001130698
TRPC3
transient receptor potential cation channel, subfamily C, member 3
chr17_+_56832492 1.685 TBX2
T-box 2
chr9_+_966963 1.681 NM_021240
DMRT3
doublesex and mab-3 related transcription factor 3
chr2_+_172658453 1.677 NM_001038493
NM_178120
DLX1

distal-less homeobox 1

chr11_+_63815348 1.674 NM_033310
KCNK4
potassium channel, subfamily K, member 4
chr8_+_56177567 1.671 NM_052898
XKR4
XK, Kell blood group complex subunit-related family, member 4
chr2_+_176702667 1.669 NM_019558
HOXD8
homeobox D8
chr14_+_89597860 1.667 NM_022054
KCNK13
potassium channel, subfamily K, member 13
chr3_+_50687675 1.666 NM_004947
DOCK3
dedicator of cytokinesis 3
chr22_-_43783449 1.665 PHF21B
PHD finger protein 21B
chr8_-_71146022 1.663 PRDM14
PR domain containing 14
chr7_-_27206249 1.662 NM_000522
HOXA13
homeobox A13
chr16_+_162845 1.660 NM_000517
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr10_+_29006425 1.659 NM_012342
BAMBI
BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)
chr10_+_115793795 1.654 NM_000684
ADRB1
adrenergic, beta-1-, receptor
chr1_-_111019051 1.653


chr3_-_50515857 1.651 NM_001005505
NM_001174051
NM_006030
CACNA2D2


calcium channel, voltage-dependent, alpha 2/delta subunit 2


chr10_+_101079099 1.643 CNNM1
cyclin M1
chr13_+_87122778 1.643 NM_015567
SLITRK5
SLIT and NTRK-like family, member 5
chr14_+_28306633 1.641 FOXG1
forkhead box G1
chr18_+_46340400 1.633 NM_002747
MAPK4
mitogen-activated protein kinase 4
chr11_-_6633427 1.633 NM_003737
DCHS1
dachsous 1 (Drosophila)
chr21_+_36993860 1.629 NM_005069
NM_009586
SIM2

single-minded homolog 2 (Drosophila)

chr17_-_76064842 1.628 NM_002522
NPTX1
neuronal pentraxin I
chr7_-_45927263 1.628 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr16_+_52877009 1.623


chr3_-_129690056 1.620 NM_001145661
GATA2
GATA binding protein 2
chr4_+_42094612 1.618 NM_001080505
SHISA3
shisa homolog 3 (Xenopus laevis)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.08 8.18e-26 GO:0009987 cellular process
1.27 4.91e-14 GO:0007399 nervous system development
1.26 8.57e-14 GO:0009653 anatomical structure morphogenesis
1.19 9.58e-14 GO:0071842 cellular component organization at cellular level
1.17 1.17e-13 GO:0016043 cellular component organization
1.11 1.22e-13 GO:0044237 cellular metabolic process
1.10 1.90e-13 GO:0050794 regulation of cellular process
1.19 2.74e-13 GO:0071841 cellular component organization or biogenesis at cellular level
1.16 3.33e-13 GO:0071840 cellular component organization or biogenesis
1.14 5.45e-13 GO:0044260 cellular macromolecule metabolic process
1.09 2.69e-12 GO:0065007 biological regulation
1.09 8.82e-12 GO:0050789 regulation of biological process
1.15 9.98e-12 GO:0032502 developmental process
1.32 2.93e-11 GO:0022008 neurogenesis
1.32 3.04e-11 GO:0048699 generation of neurons
1.16 8.94e-11 GO:0048856 anatomical structure development
1.20 9.28e-11 GO:0048523 negative regulation of cellular process
1.09 6.16e-10 GO:0008152 metabolic process
1.14 8.42e-10 GO:0007275 multicellular organismal development
1.33 4.19e-09 GO:0030182 neuron differentiation
1.17 4.61e-09 GO:0048519 negative regulation of biological process
1.15 1.11e-08 GO:0048731 system development
1.32 1.80e-08 GO:0009790 embryo development
1.11 1.93e-08 GO:0043170 macromolecule metabolic process
1.09 2.26e-08 GO:0044238 primary metabolic process
1.33 5.92e-08 GO:0032989 cellular component morphogenesis
1.37 6.08e-08 GO:0000904 cell morphogenesis involved in differentiation
1.18 8.25e-08 GO:0030154 cell differentiation
1.20 8.40e-08 GO:0006996 organelle organization
1.17 2.03e-07 GO:0048869 cellular developmental process
1.33 2.22e-07 GO:0000902 cell morphogenesis
1.13 2.36e-07 GO:0006807 nitrogen compound metabolic process
1.16 2.95e-07 GO:0048522 positive regulation of cellular process
1.26 3.77e-07 GO:0048468 cell development
1.12 4.84e-07 GO:0051179 localization
1.14 6.67e-07 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.13 8.65e-07 GO:0034641 cellular nitrogen compound metabolic process
1.31 9.49e-07 GO:0030030 cell projection organization
1.34 1.87e-06 GO:0007417 central nervous system development
1.31 9.86e-06 GO:0048666 neuron development
1.14 1.72e-05 GO:0044267 cellular protein metabolic process
1.34 1.94e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
1.30 2.02e-05 GO:0000278 mitotic cell cycle
1.15 3.17e-05 GO:0090304 nucleic acid metabolic process
1.32 3.66e-05 GO:0031175 neuron projection development
1.32 5.38e-05 GO:0072358 cardiovascular system development
1.32 5.38e-05 GO:0072359 circulatory system development
1.37 5.64e-05 GO:0051301 cell division
1.13 7.17e-05 GO:0048518 positive regulation of biological process
1.33 8.22e-05 GO:0048812 neuron projection morphogenesis
1.21 8.35e-05 GO:0010941 regulation of cell death
1.33 1.22e-04 GO:0007409 axonogenesis
1.44 1.35e-04 GO:0051129 negative regulation of cellular component organization
1.30 1.35e-04 GO:0048858 cell projection morphogenesis
1.15 1.63e-04 GO:0006464 protein modification process
1.21 1.79e-04 GO:0043067 regulation of programmed cell death
1.30 2.23e-04 GO:0032990 cell part morphogenesis
1.20 2.90e-04 GO:0042981 regulation of apoptosis
1.11 3.59e-04 GO:0051234 establishment of localization
1.14 4.06e-04 GO:0043412 macromolecule modification
1.56 5.29e-04 GO:0030111 regulation of Wnt receptor signaling pathway
1.42 6.21e-04 GO:0048568 embryonic organ development
1.20 6.52e-04 GO:0007049 cell cycle
1.35 9.85e-04 GO:0007411 axon guidance
1.11 2.08e-03 GO:0006810 transport
1.32 2.12e-03 GO:0007420 brain development
1.09 3.09e-03 GO:0023052 signaling
1.28 3.14e-03 GO:0048646 anatomical structure formation involved in morphogenesis
1.10 3.61e-03 GO:0060255 regulation of macromolecule metabolic process
1.22 3.69e-03 GO:2000026 regulation of multicellular organismal development
1.24 4.13e-03 GO:0051726 regulation of cell cycle
1.16 5.10e-03 GO:0051641 cellular localization
1.10 5.20e-03 GO:0019538 protein metabolic process
1.20 5.91e-03 GO:0016265 death
1.20 6.23e-03 GO:0008219 cell death
1.18 7.01e-03 GO:0008104 protein localization
1.16 7.17e-03 GO:0033036 macromolecule localization
1.20 7.47e-03 GO:0051128 regulation of cellular component organization
1.30 7.81e-03 GO:0009792 embryo development ending in birth or egg hatching
1.30 8.05e-03 GO:0043009 chordate embryonic development
1.30 8.05e-03 GO:0048598 embryonic morphogenesis
1.33 8.51e-03 GO:0051325 interphase
1.22 8.74e-03 GO:0022403 cell cycle phase
1.34 9.27e-03 GO:0001944 vasculature development
1.14 9.73e-03 GO:0023051 regulation of signaling
1.20 9.83e-03 GO:0022402 cell cycle process
1.38 9.95e-03 GO:0002009 morphogenesis of an epithelium
1.86 1.13e-02 GO:0030177 positive regulation of Wnt receptor signaling pathway
1.19 1.17e-02 GO:0006351 transcription, DNA-dependent
1.08 1.19e-02 GO:0019222 regulation of metabolic process
1.14 1.19e-02 GO:0034645 cellular macromolecule biosynthetic process
1.09 1.23e-02 GO:0080090 regulation of primary metabolic process
1.09 1.26e-02 GO:0007165 signal transduction
1.25 1.55e-02 GO:0007010 cytoskeleton organization
1.36 1.92e-02 GO:0003002 regionalization
1.32 2.06e-02 GO:0051329 interphase of mitotic cell cycle
1.09 2.27e-02 GO:0031323 regulation of cellular metabolic process
1.08 2.31e-02 GO:0051716 cellular response to stimulus
1.13 2.63e-02 GO:0009059 macromolecule biosynthetic process
1.21 2.66e-02 GO:0045595 regulation of cell differentiation
1.22 2.98e-02 GO:0009887 organ morphogenesis
1.18 3.01e-02 GO:0050793 regulation of developmental process
1.38 3.65e-02 GO:0045664 regulation of neuron differentiation
1.30 4.36e-02 GO:0060284 regulation of cell development
1.13 4.47e-02 GO:0016070 RNA metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.08 7.42e-27 GO:0044424 intracellular part
1.08 2.27e-26 GO:0005622 intracellular
1.10 4.55e-23 GO:0005737 cytoplasm
1.08 1.54e-17 GO:0043226 organelle
1.09 2.19e-17 GO:0043227 membrane-bounded organelle
1.08 3.96e-17 GO:0043229 intracellular organelle
1.09 4.10e-17 GO:0043231 intracellular membrane-bounded organelle
1.10 7.18e-12 GO:0044444 cytoplasmic part
1.09 5.59e-08 GO:0005634 nucleus
1.08 1.26e-06 GO:0044446 intracellular organelle part
1.08 1.74e-06 GO:0044422 organelle part
1.14 2.64e-05 GO:0044428 nuclear part
1.02 1.10e-04 GO:0005623 cell
1.02 1.27e-04 GO:0044464 cell part
1.13 1.33e-04 GO:0005829 cytosol
1.43 8.46e-04 GO:0031252 cell leading edge
1.10 1.46e-03 GO:0043234 protein complex
1.12 1.71e-03 GO:0070013 intracellular organelle lumen
1.12 3.62e-03 GO:0031981 nuclear lumen
1.11 4.34e-03 GO:0031090 organelle membrane
1.11 4.76e-03 GO:0043233 organelle lumen
1.11 6.56e-03 GO:0031974 membrane-enclosed lumen
1.13 6.75e-03 GO:0012505 endomembrane system
1.10 6.91e-03 GO:0043228 non-membrane-bounded organelle
1.10 6.91e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.16 1.31e-02 GO:0005794 Golgi apparatus
1.08 3.87e-02 GO:0032991 macromolecular complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.13 1.33e-27 GO:0005515 protein binding
1.06 4.45e-14 GO:0005488 binding
1.33 5.02e-06 GO:0019904 protein domain specific binding
1.08 1.29e-04 GO:0003824 catalytic activity
1.12 5.22e-04 GO:0000166 nucleotide binding
1.13 1.14e-03 GO:0017076 purine nucleotide binding
1.19 1.16e-03 GO:0001071 nucleic acid binding transcription factor activity
1.19 1.16e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.18 1.28e-03 GO:0030528 transcription regulator activity
1.13 1.30e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.13 1.30e-03 GO:0032553 ribonucleotide binding
1.13 1.30e-03 GO:0032555 purine ribonucleotide binding
1.20 5.64e-03 GO:0019899 enzyme binding
1.28 3.04e-02 GO:0016563 transcription activator activity
1.12 3.16e-02 GO:0016740 transferase activity
1.19 4.27e-02 GO:0043565 sequence-specific DNA binding